Pan troglodytes      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pat-0587
ENSPTRG00000049288.1
2
LLPS-Pat-0920
ENSPTRG00000034171.3
A0A2I3T8Q0
BAHCC1
3
LLPS-Pat-3494
ENSPTRG00000045198.1
A0A2I3TW06
CASP8AP2
4
LLPS-Pat-0029
ENSPTRG00000006651.4
H2Q8T2
CPSF2
5
LLPS-Pat-1457
ENSPTRG00000011638.3
G2HFH0
CPSF3
6
LLPS-Pat-1823
ENSPTRG00000019453.6
H2QV04
CPSF4
7
LLPS-Pat-3169
ENSPTRG00000008235.7
H2QBB9
CTCF
8
LLPS-Pat-0112
ENSPTRG00000023779.4
K7D8C0
CTR9
9
LLPS-Pat-2847
ENSPTRG00000001105.5
H2PZN7
DDX20
10
LLPS-Pat-2384
ENSPTRG00000016060.7
K7CRR8
FIP1L1
11
LLPS-Pat-3311
ENSPTRG00000001433.7
A0A2I3S1R0
GON4L
12
LLPS-Pat-2113
ENSPTRG00000019153.6
H2QUI9
H2AFV
13
LLPS-Pat-2160
ENSPTRG00000004372.3
A0A2I3RNZ2
HINFP
14
LLPS-Pat-0852
ENSPTRG00000000539.3
H2PYN4
LSM10
15
LLPS-Pat-3481
ENSPTRG00000017474.5
H2QRW9
LSM11
16
LLPS-Pat-2148
ENSPTRG00000004248.6
H2Q4Q0
NPAT
17
LLPS-Pat-3032
ENSPTRG00000011169.5
A0A2I3RIF7
SYMPK
18
LLPS-Pat-2287
ENSPTRG00000008703.7
H2QC53
TP53