Ovis aries      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 16 genes.  Reviewed (0 or Unreviewed (16

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ova-3903
ENSOARG00000018651.1
W5QBD4
BAHCC1
2
LLPS-Ova-1345
ENSOARG00000012409.1
W5PS72
CASP8AP2
3
LLPS-Ova-0980
ENSOARG00000012889.1
W5PTM6
CPSF2
4
LLPS-Ova-2762
ENSOARG00000015073.1
W5Q0D9
CPSF3
5
LLPS-Ova-0632
ENSOARG00000018668.1
W5QBE5
CPSF4
6
LLPS-Ova-1913
ENSOARG00000003053.1
W5NYK0
CTCF
7
LLPS-Ova-1335
ENSOARG00000010482.1
W5PLD2
CTR9
8
LLPS-Ova-2471
ENSOARG00000019651.1
W5QEF8
DDX20
9
LLPS-Ova-0822
ENSOARG00000018767.1
W5QBR1
FIP1L1
10
LLPS-Ova-3940
ENSOARG00000004747.1
W5P3U6
GON4L
11
LLPS-Ova-3090
ENSOARG00000014302.1
W5PY18
H2AFV
12
LLPS-Ova-1298
ENSOARG00000013643.1
W5PW01
HINFP
13
LLPS-Ova-2875
ENSOARG00000009596.1
W5PIM2
LSM10
14
LLPS-Ova-0006
ENSOARG00000011428.1
W5PP74
NPAT
15
LLPS-Ova-3431
ENSOARG00000010349.1
W5PKX7
SYMPK
16
LLPS-Ova-1677
ENSOARG00000015571.1
C3VC56
TP53