Ostreococcus lucimarinus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Osl-0195
OSTLU_119619
A4RSQ1
H2A
2
LLPS-Osl-0020
OSTLU_10510
A4RX17
OSTLU_10510
3
LLPS-Osl-0073
OSTLU_12108
A4RR19
OSTLU_12108
4
LLPS-Osl-0376
OSTLU_14530
A4RU45
OSTLU_14530
5
LLPS-Osl-1195
OSTLU_33504
A4S2M5
OSTLU_33504
6
LLPS-Osl-0328
OSTLU_50104
A4RZM9
OSTLU_50104
7
LLPS-Osl-0595
OSTLU_87525
A4RYW8
OSTLU_87525
8
LLPS-Osl-0601
OSTLU_14940
A4RVP5
PAFC3501