※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Orl-1022	ENSORLG00000009504.2	H2M0J1
2		LLPS-Orl-2071	ENSORLG00000017922.2	H2MUG5	casp8ap2
3		LLPS-Orl-0907	ENSORLG00000013544.2	A0A3B3H813	cpsf1
4		LLPS-Orl-0039	ENSORLG00000011628.2	H2M7W9	cpsf2
5		LLPS-Orl-2567	ENSORLG00000018854.2	H2MX86	cpsf3
6		LLPS-Orl-3381	ENSORLG00000022798.1	H2MF66	cpsf4
7		LLPS-Orl-2444	ENSORLG00000007260.3	H2LSP0	ctr9
8		LLPS-Orl-0963	ENSORLG00000008949.2	H2LYK6	ddx20
9		LLPS-Orl-0919	ENSORLG00000022841.1	A0A3B3H631	H2AFZ
10		LLPS-Orl-0636	ENSORLG00000007490.2	H2LTH0	hinfp
11		LLPS-Orl-0609	ENSORLG00000008771.2	H2LY05	LOC101157282
12		LLPS-Orl-1082	ENSORLG00000004397.2	A0A3B3HPK1	LOC101159890
13		LLPS-Orl-2506	ENSORLG00000012728.3	H2MBL8	LOC101166817
14		LLPS-Orl-2318	ENSORLG00000007434.2	H2LT95	lsm11
15		LLPS-Orl-3478	ENSORLG00000015338.2	H2MKJ4	sympk
16		LLPS-Orl-3813	ENSORLG00000013686.2	A0A3B3H9D8	tnrc18