※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Orc-1442	ENSOCUG00000022109.1	G1U940
2		LLPS-Orc-2422	ENSOCUG00000001742.3	G1SG17	CASP8AP2
3		LLPS-Orc-1779	ENSOCUG00000005713.3	G1SPH7	CPSF2
4		LLPS-Orc-1534	ENSOCUG00000003728.2	G1SKA3	CPSF3
5		LLPS-Orc-1875	ENSOCUG00000002437.3	G1SHJ8	CPSF4
6		LLPS-Orc-1297	ENSOCUG00000008983.3	G1SWA5	CTCF
7		LLPS-Orc-2064	ENSOCUG00000013302.3	G1T559	CTR9
8		LLPS-Orc-0892	ENSOCUG00000025939.2	U3KNB2	DDX20
9		LLPS-Orc-2277	ENSOCUG00000000100.3	G1SCL2	FIP1L1
10		LLPS-Orc-3540	ENSOCUG00000008133.2	G1SUJ3	H2AFV
11		LLPS-Orc-1324	ENSOCUG00000010808.2	G1T008	HINFP
12		LLPS-Orc-1139	ENSOCUG00000010191.2	G1SYT8	LOC100350760
13		LLPS-Orc-0151	ENSOCUG00000005333.2	G1TSV5	LSM10
14		LLPS-Orc-1030	ENSOCUG00000011672.3	G1T1Q9	LSM11
15		LLPS-Orc-2334	ENSOCUG00000026209.2	G1THN4	NPAT
16		LLPS-Orc-0327	ENSOCUG00000005511.3	G1SP33	SYMPK