Nicotiana attenuata      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nia-0631
A4A49_31668
A0A1J6KZ39
A4A49_31668
2
LLPS-Nia-1097
A4A49_35852
A0A1J6JXZ1
A4A49_35852
3
LLPS-Nia-0594
A4A49_13741
A0A1J6IRF5
CPSF100_0
4
LLPS-Nia-1018
A4A49_31648
A0A1J6IRU5
CPSF160
5
LLPS-Nia-1245
A4A49_08998
A0A1J6J020
CPSF73-I_0
6
LLPS-Nia-2215
A4A49_31543
A0A1J6KVI6
VIP6