Myotis lucifugus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 16 genes.  Reviewed (0 or Unreviewed (16

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Myl-0129
ENSMLUG00000000667.2
G1NTV7
2
LLPS-Myl-2447
ENSMLUG00000025140.1
G1PZ51
3
LLPS-Myl-2011
ENSMLUG00000001639.2
G1NW30
CASP8AP2
4
LLPS-Myl-2217
ENSMLUG00000005570.2
G1P528
CPSF2
5
LLPS-Myl-4038
ENSMLUG00000010636.2
G1PGE9
CPSF3
6
LLPS-Myl-2670
ENSMLUG00000010980.2
G1PH56
CPSF4
7
LLPS-Myl-0739
ENSMLUG00000005216.2
G1P490
CTCF
8
LLPS-Myl-0895
ENSMLUG00000006212.2
G1P6J0
CTR9
9
LLPS-Myl-0289
ENSMLUG00000006503.2
G1P763
FIP1L1
10
LLPS-Myl-0616
ENSMLUG00000014500.2
G1PQ64
H2AFV
11
LLPS-Myl-1176
ENSMLUG00000000455.2
G1NTC1
HINFP
12
LLPS-Myl-1102
ENSMLUG00000009868.2
G1PES6
LOC102420362
13
LLPS-Myl-1959
ENSMLUG00000023895.1
G1PYE0
LSM10
14
LLPS-Myl-2239
ENSMLUG00000015930.2
G1PTG6
LSM11
15
LLPS-Myl-3550
ENSMLUG00000011122.2
G1PHJ9
NPAT
16
LLPS-Myl-3548
ENSMLUG00000001359.2
G1NVF9
SYMPK