Microbotryum violaceum      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Miv-0723
MVLG_00509
U5GZA5
MVLG_00509
2
LLPS-Miv-1562
MVLG_01838
U5H3B6
MVLG_01838
3
LLPS-Miv-0891
MVLG_02342
U5H4V7
MVLG_02342
4
LLPS-Miv-0720
MVLG_02855
U5H6F5
MVLG_02855
5
LLPS-Miv-1434
MVLG_04407
U5HB46
MVLG_04407
6
LLPS-Miv-0306
MVLG_05590
U5HEP7
MVLG_05590
7
LLPS-Miv-0021
MVLG_06211
U5HGK6
MVLG_06211