Meleagris gallopavo      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 14 genes.  Reviewed (0 or Unreviewed (14

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Meg-0285
ENSMGAG00000000803.2
G1MQA2
2
LLPS-Meg-0728
ENSMGAG00000011885.2
G1NH57
3
LLPS-Meg-2512
ENSMGAG00000005482.2
H9H0U6
4
LLPS-Meg-2587
ENSMGAG00000004962.2
G1N0A9
5
LLPS-Meg-2765
ENSMGAG00000013631.1
G1NLK5
CASP8AP2
6
LLPS-Meg-0666
ENSMGAG00000013122.1
G1NKB6
CPSF2
7
LLPS-Meg-0015
ENSMGAG00000013995.1
G1NMJ4
CPSF3
8
LLPS-Meg-2176
ENSMGAG00000004235.1
G1MYH9
CPSF4
9
LLPS-Meg-2402
ENSMGAG00000002200.2
G1MTM5
CTCF
10
LLPS-Meg-1457
ENSMGAG00000005904.2
G1N2L5
CTR9
11
LLPS-Meg-1258
ENSMGAG00000004624.1
G1MZL9
DDX20
12
LLPS-Meg-1088
ENSMGAG00000011261.1
G1NFH8
H2AFZ
13
LLPS-Meg-2967
ENSMGAG00000002682.2
G1MUS0
HINFP
14
LLPS-Meg-1254
ENSMGAG00000015707.1
G1NRI7
LSM10