Mandrillus leucophaeus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mal-1624
ENSMLEG00000034871.1
A0A2K5Z0N4
BAHCC1
2
LLPS-Mal-0622
ENSMLEG00000040162.1
A0A2K5ZVQ8
CASP8AP2
3
LLPS-Mal-1490
ENSMLEG00000043010.1
A0A2K6AD50
CPSF1
4
LLPS-Mal-1163
ENSMLEG00000029394.1
A0A2K5Y4E1
CPSF2
5
LLPS-Mal-3311
ENSMLEG00000026825.1
A0A2K5XTB9
CPSF3
6
LLPS-Mal-4168
ENSMLEG00000034721.1
A0A2K5YZY5
CPSF4
7
LLPS-Mal-1745
ENSMLEG00000041196.1
A0A2K6A1T9
CTCF
8
LLPS-Mal-2301
ENSMLEG00000026645.1
A0A2K5XSY1
CTR9
9
LLPS-Mal-0498
ENSMLEG00000005722.1
A0A2K5XDS3
DDX20
10
LLPS-Mal-0775
ENSMLEG00000041763.1
A0A2K6A5B8
FIP1L1
11
LLPS-Mal-0565
ENSMLEG00000035764.1
A0A2K5Z5X1
H2AFV
12
LLPS-Mal-0107
ENSMLEG00000042109.1
A0A2K6A7G8
HINFP
13
LLPS-Mal-1765
ENSMLEG00000025150.1
A0A2K5XR67
LSM10
14
LLPS-Mal-4224
ENSMLEG00000027420.1
A0A2K5XUG8
LSM11
15
LLPS-Mal-3028
ENSMLEG00000039127.1
A0A2K5ZQ72
NPAT
16
LLPS-Mal-2579
ENSMLEG00000040508.1
A0A2K5ZYU6
SYMPK
17
LLPS-Mal-0198
ENSMLEG00000042592.1
A0A2K6AAI9
TP53