Macaca nemestrina      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Man-0669
ENSMNEG00000040618.1
A0A2K6DGM2
BAHCC1
2
LLPS-Man-0693
ENSMNEG00000041673.1
A0A2K6DMT0
CASP8AP2
3
LLPS-Man-3440
ENSMNEG00000043564.1
A0A2K6E049
CPSF1
4
LLPS-Man-0836
ENSMNEG00000031584.1
A0A2K6BU30
CPSF2
5
LLPS-Man-0247
ENSMNEG00000039447.1
A0A2K6D8J5
CPSF3
6
LLPS-Man-1589
ENSMNEG00000032306.1
A0A2K6BYW5
CPSF4
7
LLPS-Man-3358
ENSMNEG00000036416.1
A0A2K6CQN4
CTCF
8
LLPS-Man-2280
ENSMNEG00000043569.1
A0A2K6E026
CTR9
9
LLPS-Man-0279
ENSMNEG00000005757.1
A0A2K6AQ46
DDX20
10
LLPS-Man-1262
ENSMNEG00000026332.1
A0A2K6B379
FIP1L1
11
LLPS-Man-3971
ENSMNEG00000022837.1
A0A2K6B159
GON4L
12
LLPS-Man-2090
ENSMNEG00000034878.1
A0A2K6CFZ8
H2AFV
13
LLPS-Man-1298
ENSMNEG00000040823.1
A0A2K6DHD1
HINFP
14
LLPS-Man-3373
ENSMNEG00000020023.1
A0A2K6AYR4
LSM10
15
LLPS-Man-1706
ENSMNEG00000045265.1
A0A2K6EBH1
LSM11
16
LLPS-Man-1898
ENSMNEG00000029307.1
A0A2K6BEG3
NPAT
17
LLPS-Man-3523
ENSMNEG00000019439.1
A0A2K6AYS6
SYMPK
18
LLPS-Man-3642
ENSMNEG00000038875.1
A0A2K6D4N4
TP53