Leptosphaeria maculans      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Lem-0772
LEMA_P010380.1
E5ACP9
LEMA_P010380.1
2
LLPS-Lem-0922
LEMA_P020990.1
E5ABC8
LEMA_P020990.1
3
LLPS-Lem-1560
LEMA_P023120.1
E5ABZ1
LEMA_P023120.1
4
LLPS-Lem-0754
LEMA_P025050.1
E4ZXE3
LEMA_P025050.1
5
LLPS-Lem-0623
LEMA_P027070.1
E4ZVC9
LEMA_P027070.1
6
LLPS-Lem-0299
LEMA_P028040.1
E4ZVM6
LEMA_P028040.1
7
LLPS-Lem-1442
LEMA_P087030.1
E5A769
LEMA_P087030.1