Gorilla gorilla      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gog-0045
ENSGGOG00000015576.3
G3RHS1
2
LLPS-Gog-0091
ENSGGOG00000001063.3
G3QFH5
3
LLPS-Gog-0271
ENSGGOG00000000477.3
G3QDY9
4
LLPS-Gog-0316
ENSGGOG00000001757.3
G3QHA7
5
LLPS-Gog-1138
ENSGGOG00000011799.3
G3R814
6
LLPS-Gog-1280
ENSGGOG00000027801.2
A0A2I2YTF8
7
LLPS-Gog-1651
ENSGGOG00000003556.3
G3QLX0
8
LLPS-Gog-1681
ENSGGOG00000012653.3
G3S927
9
LLPS-Gog-2363
ENSGGOG00000003410.3
G3QLK1
10
LLPS-Gog-2365
ENSGGOG00000017136.3
G3RLR0
11
LLPS-Gog-2392
ENSGGOG00000008672.3
G3S641
12
LLPS-Gog-2750
ENSGGOG00000008087.3
G3SDE8
13
LLPS-Gog-2775
ENSGGOG00000015131.3
G3RGL8
14
LLPS-Gog-3150
ENSGGOG00000016185.3
G3RJB7
15
LLPS-Gog-3697
ENSGGOG00000006427.3
G3SJN0
16
LLPS-Gog-3829
ENSGGOG00000011435.3
G3R731
17
LLPS-Gog-2759
ENSGGOG00000009786.3
A0A2I2Y7Z8
TP53