※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Fec-3806	ENSFCAG00000027150.3	A0A2I2UX30	CASP8AP2
2		LLPS-Fec-1222	ENSFCAG00000007886.5	M3W8K2	CPSF2
3		LLPS-Fec-3651	ENSFCAG00000007852.5	M3W8I0	CPSF3
4		LLPS-Fec-2192	ENSFCAG00000015070.4	A0A337RX23	CPSF4
5		LLPS-Fec-2373	ENSFCAG00000003492.5	M3W0F6	CTCF
6		LLPS-Fec-0483	ENSFCAG00000000407.5	M3VUP9	CTR9
7		LLPS-Fec-0580	ENSFCAG00000025736.3	M3XAQ7	DDX20
8		LLPS-Fec-2399	ENSFCAG00000022148.3	M3WSP6	FIP1L1
9		LLPS-Fec-0831	ENSFCAG00000010271.4	A0A2I2V4Y3	H2AFV
10		LLPS-Fec-2736	ENSFCAG00000001165.4	A0A2I2UGU2	HINFP
11		LLPS-Fec-2438	ENSFCAG00000012133.5	M3WGD9	LOC101087446
12		LLPS-Fec-3260	ENSFCAG00000001266.4	M3VWB6	LSM11
13		LLPS-Fec-3415	ENSFCAG00000012429.5	M3WGX7	NPAT
14		LLPS-Fec-1701	ENSFCAG00000007337.5	M3W7J5	SYMPK
15		LLPS-Fec-4458	ENSFCAG00000001949.4	M3VXL4	TNRC18
16		LLPS-Fec-4041	ENSFCAG00000009623.3	P41685	TP53