Equus caballus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Eqc-1370
ENSECAG00000039005.1
2
LLPS-Eqc-2230
ENSECAG00000021325.2
F6YDM6
BAHCC1
3
LLPS-Eqc-0851
ENSECAG00000006638.2
F6UGU4
CASP8AP2
4
LLPS-Eqc-0868
ENSECAG00000022209.2
F6U2K6
CPSF1
5
LLPS-Eqc-1280
ENSECAG00000023935.2
F6YTB2
CPSF2
6
LLPS-Eqc-1986
ENSECAG00000019911.2
F7CPI2
CPSF3
7
LLPS-Eqc-2535
ENSECAG00000007525.2
F7DCT2
CPSF4
8
LLPS-Eqc-0864
ENSECAG00000015924.2
F6V9V7
CTCF
9
LLPS-Eqc-2915
ENSECAG00000010969.2
F6ZY59
CTR9
10
LLPS-Eqc-0203
ENSECAG00000013565.2
F7ALE3
DDX20
11
LLPS-Eqc-2452
ENSECAG00000019415.2
F7DYB4
FIP1L1
12
LLPS-Eqc-2232
ENSECAG00000023732.2
F7BXQ8
H2AFZ
13
LLPS-Eqc-1836
ENSECAG00000024938.2
F6S9G2
HINFP
14
LLPS-Eqc-2964
ENSECAG00000019775.2
F7DHH2
LOC100057465
15
LLPS-Eqc-0217
ENSECAG00000005071.2
F6RB14
LSM10
16
LLPS-Eqc-2958
ENSECAG00000008226.2
F6W4F0
NPAT
17
LLPS-Eqc-0105
ENSECAG00000008163.2
F6W3K7
SYMPK
18
LLPS-Eqc-0097
ENSECAG00000008126.2
P79892
TP53