Danio rerio      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dar-0116
ENSDARG00000101222.2
A0A2R8Q4W4
2
LLPS-Dar-0086
ENSDARG00000022718.10
F1QD18
casp8ap2
3
LLPS-Dar-1405
ENSDARG00000034178.12
A0A0R4IC37
cpsf1
4
LLPS-Dar-0775
ENSDARG00000028971.7
F1QVV4
cpsf2
5
LLPS-Dar-0805
ENSDARG00000027649.8
Q5U3T4
cpsf3
6
LLPS-Dar-2260
ENSDARG00000020217.6
F1Q949
cpsf4
7
LLPS-Dar-0546
ENSDARG00000056621.8
A0A2R8QUZ1
ctcf
8
LLPS-Dar-2654
ENSDARG00000009170.10
A3KDM3
ctr9
9
LLPS-Dar-0359
ENSDARG00000061204.9
P0C218
ddx20
10
LLPS-Dar-2878
ENSDARG00000070431.5
Q5XJD3
fip1l1
11
LLPS-Dar-3111
ENSDARG00000005867.13
F1QI87
gon4l
12
LLPS-Dar-3247
ENSDARG00000068820.6
Q71PD7
h2afv
13
LLPS-Dar-1809
ENSDARG00000004851.10
A2BFS7
hinfp
14
LLPS-Dar-2551
ENSDARG00000090854.3
E9QIK5
lsm11
15
LLPS-Dar-0994
ENSDARG00000055548.8
A0A0R4IH22
npat
16
LLPS-Dar-0142
ENSDARG00000059553.9
A0A0R4I9D6
sympk
17
LLPS-Dar-4218
ENSDARG00000077052.6
X1WHA2
tnrc18
18
LLPS-Dar-2314
ENSDARG00000115148.1
P79734
tp53