Cyanidioschyzon merolae      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cym-0250
CMF161C
M1VB83
CYME_CMF161C
2
LLPS-Cym-0858
CMF174C
M1UPX3
CYME_CMF174C
3
LLPS-Cym-0470
CMH020C
M1V4X0
CYME_CMH020C
4
LLPS-Cym-0264
CMQ077C
M1VKH3
CYME_CMQ077C
5
LLPS-Cym-0507
CMR160C
M1V6R2
CYME_CMR160C
6
LLPS-Cym-0658
CMR457C
M1UWK2
CYME_CMR457C
7
LLPS-Cym-0001
CMS297C
M1VM14
CYME_CMS297C