※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Cii-0536	ENSCING00000024984.1	H2Y1I9
2		LLPS-Cii-0693	ENSCING00000008994.3	F6PKD1
3		LLPS-Cii-0862	ENSCING00000001603.3	F6RZS3
4		LLPS-Cii-1144	ENSCING00000003483.3	F6UA38
5		LLPS-Cii-1255	ENSCING00000024005.1	H2XL75
6		LLPS-Cii-1558	ENSCING00000000514.3	F6V136
7		LLPS-Cii-1926	ENSCING00000021080.1	H2XUQ0
8		LLPS-Cii-2076	ENSCING00000022432.1	H2XXA9
9		LLPS-Cii-0796	ENSCING00000005798.3	F6RLX1	LOC100183843
10		LLPS-Cii-0351	ENSCING00000007214.3	F6W785	LOC100184465
11		LLPS-Cii-1358	ENSCING00000002109.3	F6ZR96	LOC100185308
12		LLPS-Cii-0022	ENSCING00000007881.3	F6TGK6	LOC113474389
13		LLPS-Cii-0138	ENSCING00000006765.3	H2XNG3	zf(c2h2)-30