Chondrus crispus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Chc-0654
CHC_T00008850001
R7QA63
CHC_T00008850001
2
LLPS-Chc-0749
CHC_T00010011001
R7Q5H0
CHC_T00010011001
3
LLPS-Chc-0765
CHC_T00010067001
R7QPX5
CHC_T00010067001
4
LLPS-Chc-0694
CHC_T00010199001
R7QCT1
CHC_T00010199001
5
LLPS-Chc-0222
CHC_T00010227001
R7Q2C5
CHC_T00010227001
6
LLPS-Chc-0175
CHC_T00010348001
R7QPH3
CHC_T00010348001