Cercocebus atys      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cea-1088
ENSCATG00000031480.1
A0A2K5LQ71
BAHCC1
2
LLPS-Cea-2364
ENSCATG00000014543.1
A0A2K5KT80
CASP8AP2
3
LLPS-Cea-0586
ENSCATG00000037234.1
A0A2K5MRL0
CPSF1
4
LLPS-Cea-1441
ENSCATG00000030132.1
A0A2K5LG03
CPSF2
5
LLPS-Cea-0477
ENSCATG00000014770.1
A0A2K5KWH6
CPSF3
6
LLPS-Cea-2642
ENSCATG00000038440.1
A0A2K5MZ68
CPSF4
7
LLPS-Cea-0555
ENSCATG00000042738.1
A0A2K5NS86
CTCF
8
LLPS-Cea-1498
ENSCATG00000033343.1
A0A2K5M1N2
CTR9
9
LLPS-Cea-2699
ENSCATG00000039030.1
A0A2K5N3E2
DDX20
10
LLPS-Cea-1022
ENSCATG00000041740.1
A0A2K5NKM6
FIP1L1
11
LLPS-Cea-2124
ENSCATG00000031497.1
A0A2K5LRS2
GON4L
12
LLPS-Cea-3074
ENSCATG00000001553.1
A0A2K5KI01
H2AFV
13
LLPS-Cea-3460
ENSCATG00000044477.1
A0A2K5P2P8
HINFP
14
LLPS-Cea-1094
ENSCATG00000006589.1
A0A2K5KL39
LSM10
15
LLPS-Cea-0353
ENSCATG00000042524.1
A0A2K5NQQ5
LSM11
16
LLPS-Cea-0325
ENSCATG00000008696.1
A0A2K5KMK7
NPAT
17
LLPS-Cea-3467
ENSCATG00000045107.1
A0A2K5P6U4
SYMPK
18
LLPS-Cea-1132
ENSCATG00000039093.1
A0A2K5N3Z0
TP53