Cavia porcellus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cap-1267
ENSCPOG00000007113.4
A0A286XEF9
BAHCC1
2
LLPS-Cap-0820
ENSCPOG00000004110.4
H0V2E9
CASP8AP2
3
LLPS-Cap-1097
ENSCPOG00000011448.4
H0VJ73
CPSF1
4
LLPS-Cap-1057
ENSCPOG00000010899.4
H0VHZ1
CPSF2
5
LLPS-Cap-2130
ENSCPOG00000011299.4
H0VIV6
CPSF3
6
LLPS-Cap-0873
ENSCPOG00000001783.4
A0A286XUE3
CPSF4
7
LLPS-Cap-1452
ENSCPOG00000010698.4
H0VHG7
CTCF
8
LLPS-Cap-1680
ENSCPOG00000009018.4
H0VDN6
CTR9
9
LLPS-Cap-1017
ENSCPOG00000032340.1
A0A286XMK9
DDX20
10
LLPS-Cap-3889
ENSCPOG00000010770.4
A0A286XXV1
Fip1l1
11
LLPS-Cap-1975
ENSCPOG00000004859.4
H0V441
Gon4l
12
LLPS-Cap-0543
ENSCPOG00000036358.1
H0UUP0
H2AFV
13
LLPS-Cap-4272
ENSCPOG00000006488.4
H0V7W6
HINFP
14
LLPS-Cap-0165
ENSCPOG00000039302.1
A0A286XIA4
LSM10
15
LLPS-Cap-3823
ENSCPOG00000000906.4
H0UV03
LSM11
16
LLPS-Cap-1487
ENSCPOG00000010522.4
H0VH30
NPAT
17
LLPS-Cap-2154
ENSCPOG00000010434.4
H0VGW0
SYMPK
18
LLPS-Cap-3698
ENSCPOG00000014252.4
Q9WUR6
TP53