Callithrix jacchus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Caj-3824
ENSCJAG00000007971.3
F7IKZ8
BAHCC1
2
LLPS-Caj-1883
ENSCJAG00000000992.3
F6YDZ4
CASP8AP2
3
LLPS-Caj-0490
ENSCJAG00000021421.3
U3CFH4
CPSF1
4
LLPS-Caj-0024
ENSCJAG00000018069.3
F6R015
CPSF2
5
LLPS-Caj-1522
ENSCJAG00000006276.3
F7HIE0
CPSF3
6
LLPS-Caj-4198
ENSCJAG00000015826.2
U3BK11
CPSF4
7
LLPS-Caj-2270
ENSCJAG00000016139.3
F7IC32
CTCF
8
LLPS-Caj-2539
ENSCJAG00000010795.2
F7D3T8
CTR9
9
LLPS-Caj-0391
ENSCJAG00000013428.3
F6S3C8
DDX20
10
LLPS-Caj-3092
ENSCJAG00000018490.3
U3D9W1
FIP1L1
11
LLPS-Caj-0921
ENSCJAG00000007977.3
F7HUX6
GON4L
12
LLPS-Caj-1078
ENSCJAG00000011953.3
U3EEU6
H2AFV
13
LLPS-Caj-2829
ENSCJAG00000013942.3
F7AEP4
HINFP
14
LLPS-Caj-1127
ENSCJAG00000044880.1
U3DG41
LSM10
15
LLPS-Caj-0301
ENSCJAG00000018985.3
F7II80
LSM11
16
LLPS-Caj-3956
ENSCJAG00000010132.3
F7GIN2
NPAT
17
LLPS-Caj-3648
ENSCJAG00000012172.4
F7HNG7
SYMPK
18
LLPS-Caj-2951
ENSCJAG00000014978.3
F7GNX0
TP53