Brachypodium distachyon      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Brd-1617
BRADI_2g47267v3
A0A0Q3R7M4
100827067
2
LLPS-Brd-0901
BRADI_5g04673v3
I1IWJ9
100831691
3
LLPS-Brd-1327
BRADI_2g00840v3
A0A2K2D6B7
100835825
4
LLPS-Brd-0117
BRADI_3g12240v3
I1I010
100836474
5
LLPS-Brd-0674
BRADI_1g09065v3
I1GNF9
100840870
6
LLPS-Brd-0688
BRADI_1g01140v3
A0A0Q3GLS3
100846455