Bos taurus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Bot-3328
ENSBTAG00000016776.6
F1MM81
BAHCC1
2
LLPS-Bot-3492
ENSBTAG00000011313.6
E1BLU4
CASP8AP2
3
LLPS-Bot-0089
ENSBTAG00000008355.6
Q10569
CPSF1
4
LLPS-Bot-1648
ENSBTAG00000010227.3
Q10568
CPSF2
5
LLPS-Bot-3108
ENSBTAG00000019735.5
P79101
CPSF3
6
LLPS-Bot-1685
ENSBTAG00000002090.6
O19137
CPSF4
7
LLPS-Bot-1286
ENSBTAG00000013757.6
Q08DH9
CTCF
8
LLPS-Bot-0267
ENSBTAG00000015566.6
F1N4V2
CTR9
9
LLPS-Bot-2030
ENSBTAG00000018717.6
F1MRW7
DDX20
10
LLPS-Bot-1538
ENSBTAG00000020653.6
E1BKM0
FIP1L1
11
LLPS-Bot-4192
ENSBTAG00000020356.6
F1MP31
GON4L
12
LLPS-Bot-3797
ENSBTAG00000016975.4
Q32LA7
H2AFV
13
LLPS-Bot-2197
ENSBTAG00000015015.5
F1MZ17
HINFP
14
LLPS-Bot-0680
ENSBTAG00000024096.5
A4IFN1
LSM10
15
LLPS-Bot-3966
ENSBTAG00000010363.6
F1MKH0
LSM11
16
LLPS-Bot-4642
ENSBTAG00000010286.5
F1MHZ3
NPAT
17
LLPS-Bot-3131
ENSBTAG00000012101.6
E1BJF6
SYMPK
18
LLPS-Bot-3076
ENSBTAG00000001069.4
P67939
TP53