Astyanax mexicanus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asm-0160
ENSAMXG00000040738.1
A0A3B1IRP9
2
LLPS-Asm-0369
ENSAMXG00000004786.2
A0A3B1K278
3
LLPS-Asm-0493
ENSAMXG00000033820.1
A0A3B1JAQ1
4
LLPS-Asm-0974
ENSAMXG00000020494.2
W5LMP8
5
LLPS-Asm-1016
ENSAMXG00000011126.2
W5KV29
6
LLPS-Asm-1157
ENSAMXG00000014316.2
W5L4H0
7
LLPS-Asm-1302
ENSAMXG00000010115.2
A0A3B1IMM2
8
LLPS-Asm-1424
ENSAMXG00000018377.2
A0A3B1KCY5
9
LLPS-Asm-1444
ENSAMXG00000018696.2
W5LHE9
10
LLPS-Asm-1561
ENSAMXG00000008485.2
W5KMF3
11
LLPS-Asm-1698
ENSAMXG00000008546.2
A0A3B1JFR7
12
LLPS-Asm-1729
ENSAMXG00000031647.1
A0A3B1K266
13
LLPS-Asm-2275
ENSAMXG00000003514.2
W5K7M7
14
LLPS-Asm-2766
ENSAMXG00000010162.2
W5KS96
15
LLPS-Asm-2799
ENSAMXG00000041225.1
A0A3B1IZN4
16
LLPS-Asm-3183
ENSAMXG00000013677.2
A0A3B1JS15
17
LLPS-Asm-3336
ENSAMXG00000025301.2
W5LSQ2
18
LLPS-Asm-0179
ENSAMXG00000036471.1
A0A3B1ISR8
H2AFZ