Aspergillus oryzae      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aso-1129
AO090005001001
Q2UR24
AO090005001001
2
LLPS-Aso-0294
AO090005001277
Q2UQF0
AO090005001277
3
LLPS-Aso-0956
AO090009000677
Q2UTM1
AO090009000677
4
LLPS-Aso-0368
AO090103000017
Q2TZ19
cft1
5
LLPS-Aso-0144
AO090003001324
Q2UJ80
HTZ1
6
LLPS-Aso-1285
AO090005000813
Q2URI6
yth1