Aspergillus flavus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asf-1077
AFLA_012110
B8NYP1
AFLA_012110
2
LLPS-Asf-1036
AFLA_025080
B8N2Y4
AFLA_025080
3
LLPS-Asf-0354
AFLA_048320
B8NSG9
AFLA_048320
4
LLPS-Asf-1004
AFLA_080640
B8MYC7
AFLA_080640
5
LLPS-Asf-0772
AFLA_082550
B8MYW6
AFLA_082550
6
LLPS-Asf-0255
AFLA_085110
B8MZM1
AFLA_085110
7
LLPS-Asf-0715
AFLA_106320
B8N838
AFLA_106320