Aspergillus clavatus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asc-0331
ACLA_009130
A1C9S5
ACLA_009130
2
LLPS-Asc-1140
ACLA_018680
A1CNE3
ACLA_018680
3
LLPS-Asc-0142
ACLA_031620
A1CS08
ACLA_031620
4
LLPS-Asc-1335
ACLA_037490
A1CK68
ACLA_037490
5
LLPS-Asc-0782
ACLA_084420
A1CTW0
ACLA_084420
6
LLPS-Asc-0283
ACLA_057370
A1C3U1
cft1
7
LLPS-Asc-0247
ACLA_003310
A1C5F1
HTZ1