Ashbya gossypii      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asg-1044
AGOS_AGL182C
Q750X1
AGOS_AGL182C
2
LLPS-Asg-0654
AGOS_AGR398W
Q74Z09
AGOS_AGR398W
3
LLPS-Asg-0430
AGOS_AAL060W
Q75EY8
CFT1
4
LLPS-Asg-0082
AGOS_AGL307W
Q751K8
FIP1
5
LLPS-Asg-0506
AGOS_ACL017C
Q75CC6
HTZ1
6
LLPS-Asg-1077
AGOS_AGR279C
Q74ZC0
YSH1
7
LLPS-Asg-0491
AGOS_AEL331W
Q758T3
YTH1