Absidia glauca      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Abg-0403
SAL96565
A0A163J1E4
ABSGL_01981.1 scaffold 2596
2
LLPS-Abg-1321
SAL97560
A0A168LV80
ABSGL_03058.1 scaffold 4127
3
LLPS-Abg-1540
SAL98538
A0A168MHW1
ABSGL_04087.1 scaffold 5027
4
LLPS-Abg-1219
SAL99458
A0A168MYL5
ABSGL_05072.1 scaffold 6272
5
LLPS-Abg-0412
SAM01075
A0A168NRU4
ABSGL_06812.1 scaffold 8678
6
LLPS-Abg-0186
SAM01098
A0A168NS90
ABSGL_06835.1 scaffold 8678
7
LLPS-Abg-1544
SAM04133
A0A163K445
ABSGL_09993.1 scaffold 11783
8
LLPS-Abg-0456
SAM04948
A0A168QKH6
ABSGL_10814.1 scaffold 12033
9
LLPS-Abg-0991
SAM04956
A0A163JV90
ABSGL_10822.1 scaffold 12033