Tursiops truncatus      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tut-2254
ENSTTRG00000003065.1
A0A2U3V747
GEMIN4
2
LLPS-Tut-0476
ENSTTRG00000014326.1
A0A2U3V5Q9
GEMIN6
3
LLPS-Tut-0105
ENSTTRG00000009266.1
A0A2U4AJJ9
GEMIN8
4
LLPS-Tut-1371
ENSTTRG00000017099.1
A0A2U4APC1
LOC101323006
5
LLPS-Tut-0533
ENSTTRG00000003466.1
A0A2U4BHF6
STRAP
6
LLPS-Tut-0706
ENSTTRG00000014145.1
A0A2U4C6P7
TAF15
7
LLPS-Tut-0807
ENSTTRG00000001312.1
A0A2U4AZQ2
TARDBP