Tetraodon nigroviridis      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ten-0292
ENSTNIG00000011303.1
H3D156
2
LLPS-Ten-0982
ENSTNIG00000014758.1
H3DBA3
3
LLPS-Ten-1433
ENSTNIG00000007236.1
H3CP56
4
LLPS-Ten-1452
ENSTNIG00000007625.1
H3CQA6
5
LLPS-Ten-1573
ENSTNIG00000016875.1
H3DHJ6
6
LLPS-Ten-1977
ENSTNIG00000014282.1
H3D9V5
7
LLPS-Ten-3376
ENSTNIG00000000221.1
H3C699
8
LLPS-Ten-3410
ENSTNIG00000001453.1
H3C5Q3
9
LLPS-Ten-0089
ENSTNIG00000014186.1
Q4RZG0
GSTENG00026504001
10
LLPS-Ten-0699
ENSTNIG00000019425.1
Q4RE31
GSTENG00035951001