Scophthalmus maximus      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scm-0567
ENSSMAG00000016401.1
A0A2U9BF43
SMAX5B_002184
2
LLPS-Scm-1306
ENSSMAG00000011151.1
A0A2U9CM43
SMAX5B_003461
3
LLPS-Scm-0832
ENSSMAG00000015099.1
A0A2U9B1R7
SMAX5B_007684
4
LLPS-Scm-1407
ENSSMAG00000017304.1
A0A2U9B3G8
SMAX5B_008446
5
LLPS-Scm-2585
ENSSMAG00000010187.1
A0A2U9B706
SMAX5B_010681
6
LLPS-Scm-3047
ENSSMAG00000007922.1
A0A2U9BRS0
SMAX5B_010994
7
LLPS-Scm-1169
ENSSMAG00000013978.1
A0A2U9CNN5
SMAX5B_013018
8
LLPS-Scm-1551
ENSSMAG00000014017.1
A0F019
SMAX5B_013326
9
LLPS-Scm-0976
ENSSMAG00000021084.1
A0A2U9BM96
SMAX5B_021606
10
LLPS-Scm-0288
ENSSMAG00000014019.1
A0A2U9AWG2
SMAX5B_022033