Scleropages formosus      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scf-1289
ENSSFOG00015021904.1
A0A0P7ZGV4
Z043_100095
2
LLPS-Scf-0258
ENSSFOG00015015430.1
A0A0P7X9X5
Z043_107708
3
LLPS-Scf-3825
ENSSFOG00015023420.1
A0A0P7V1F3
Z043_113235
4
LLPS-Scf-3462
ENSSFOG00015010763.1
A0A0P7UTA2
Z043_116379
5
LLPS-Scf-2390
ENSSFOG00015015840.1
A0A0N8JXA3
Z043_118585
6
LLPS-Scf-1179
ENSSFOG00015002287.1
A0A0P7UKI1
Z043_119755
7
LLPS-Scf-2084
ENSSFOG00015008354.1
A0A0N8JWK7
Z043_120719
8
LLPS-Scf-0497
ENSSFOG00015012315.1
A0A0P7Y659
Z043_120744
9
LLPS-Scf-0923
ENSSFOG00015015507.1
A0A0P7UF11
Z043_124568