Ictalurus punctatus      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Icp-0088
ENSIPUG00000004876.1
W5UEH5
ddx20
2
LLPS-Icp-0827
ENSIPUG00000012821.1
A0A2D0RJT4
gemin2
3
LLPS-Icp-0348
ENSIPUG00000006029.1
W5U6D0
GEMIN4
4
LLPS-Icp-0622
ENSIPUG00000006460.1
W5UJZ1
Gemin5
5
LLPS-Icp-0584
ENSIPUG00000011728.1
A0A2D0RS50
gemin6
6
LLPS-Icp-3183
ENSIPUG00000004094.1
A0A2D0QSW4
gemin7
7
LLPS-Icp-2434
ENSIPUG00000013983.1
A0A2D0Q7C3
gemin8
8
LLPS-Icp-0691
ENSIPUG00000023818.1
A0A2D0RX45
LOC108271795
9
LLPS-Icp-1479
ENSIPUG00000012580.1
A0A2D0PKZ0
smn1
10
LLPS-Icp-1408
ENSIPUG00000024138.1
A0A2D0T3N4
strap