Fukomys damarensis      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Fud-0538
ENSFDAG00000001562.1
2
LLPS-Fud-3452
ENSFDAG00000017683.1
3
LLPS-Fud-3266
ENSFDAG00000019846.1
A0A091DZU2
H920_02051
4
LLPS-Fud-0631
ENSFDAG00000007552.1
A0A091EL78
H920_02319
5
LLPS-Fud-2505
ENSFDAG00000004461.1
A0A091DTJ3
H920_04936
6
LLPS-Fud-1408
ENSFDAG00000004675.1
A0A091DKG3
H920_06978
7
LLPS-Fud-2380
ENSFDAG00000001208.1
A0A091DUU3
H920_11960
8
LLPS-Fud-2999
ENSFDAG00000013830.1
A0A091D2C7
H920_12381
9
LLPS-Fud-4225
ENSFDAG00000000162.1
A0A091D0C3
H920_13042
10
LLPS-Fud-1162
ENSFDAG00000011157.1
A0A091CX82
H920_15313
11
LLPS-Fud-0774
ENSFDAG00000007127.1
A0A091CPW8
H920_19315