Chlorocebus sabaeus      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Chs-0484
ENSCSAG00000015688.1
A0A0D9RT05
2
LLPS-Chs-0600
ENSCSAG00000000785.1
A0A0D9S8N2
3
LLPS-Chs-0739
ENSCSAG00000016872.1
A0A0D9RWD3
4
LLPS-Chs-1801
ENSCSAG00000019423.1
A0A0D9SDJ2
5
LLPS-Chs-1089
ENSCSAG00000001582.1
A0A0D9S6F5
DDX20
6
LLPS-Chs-1557
ENSCSAG00000005711.1
A0A0D9R082
FUS
7
LLPS-Chs-0355
ENSCSAG00000014260.1
A0A0D9RP55
GEMIN4
8
LLPS-Chs-1332
ENSCSAG00000010767.1
A0A0D9REE8
GEMIN5
9
LLPS-Chs-3019
ENSCSAG00000012310.1
A0A0D9RIR2
GEMIN6
10
LLPS-Chs-0353
ENSCSAG00000019622.1
A0A0D9SE29
GEMIN7
11
LLPS-Chs-3605
ENSCSAG00000002759.1
A0A0D9S347
SNRNP70
12
LLPS-Chs-0604
ENSCSAG00000008319.1
A0A0D9R7I5
STRAP