Aotus nancymaae      Gemini of cajal body


※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aon-0019
ENSANAG00000032133.1
A0A2K5E651
2
LLPS-Aon-1392
ENSANAG00000035249.1
A0A2K5EQY0
3
LLPS-Aon-2022
ENSANAG00000021591.1
A0A2K5CEH5
4
LLPS-Aon-0909
ENSANAG00000037881.1
A0A2K5F6N4
DDX20
5
LLPS-Aon-3883
ENSANAG00000034256.1
A0A2K5EIT2
GEMIN4
6
LLPS-Aon-2086
ENSANAG00000021595.1
A0A2K5CEL6
GEMIN5
7
LLPS-Aon-0270
ENSANAG00000034313.1
A0A2K5EJ90
GEMIN6
8
LLPS-Aon-3245
ENSANAG00000019968.1
A0A2K5C565
GEMIN7
9
LLPS-Aon-1368
ENSANAG00000037448.1
A0A2K5F3Z5
GEMIN8
10
LLPS-Aon-1066
ENSANAG00000036787.1
A0A2K5EZU8
SNRNP70
11
LLPS-Aon-1263
ENSANAG00000024138.1
A0A2K5CUR3
STRAP