※ Gemini of cajal body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Gemini of Cajal bodies, also called as Gemini of coiled bodies or nuclear gems, is a kind of these bodies located in Nucleus of spherical shape, It do not contain snRNPs. The function of nuclear gems is still unknown, may be related to further maturation, storage or recycling of splicing factors (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525

  Reviewed (0)  or Unreviewed (4) 

No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Abg-1035	SAL99637	A0A168N1S5	ABSGL_05282.1 scaffold 6884
2		LLPS-Abg-0412	SAM01075	A0A168NRU4	ABSGL_06812.1 scaffold 8678
3		LLPS-Abg-1863	SAM01366	A0A163JHM3	ABSGL_07107.1 scaffold 8717
4		LLPS-Abg-1371	SAM03290	A0A163L0Y0	ABSGL_09108.1 scaffold 10677