Yarrowia lipolytica      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Yal-0651
YALI0_D03888g
Q6CAD2
TEL1
2
LLPS-Yal-1460
YALI0_E22935g
Q6C4X6
YALI0_E22935g
3
LLPS-Yal-0630
YALI0_F15477g
Q6C1K4
YALI0_F15477g
4
LLPS-Yal-0807
YALI0_F20636g
Q6C0Z0
YALI0_F20636g