Xiphophorus maculatus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Xim-0450
ENSXMAG00000016925.2
M4AR83
2
LLPS-Xim-0887
ENSXMAG00000003129.2
M3ZLP0
3
LLPS-Xim-1040
ENSXMAG00000009281.2
M4A4B4
4
LLPS-Xim-1110
ENSXMAG00000028522.1
A0A3B5QZ48
5
LLPS-Xim-1191
ENSXMAG00000001907.2
M3ZIA5
6
LLPS-Xim-1237
ENSXMAG00000026302.1
A0A3B5R8Z1
7
LLPS-Xim-1742
ENSXMAG00000000592.2
M3ZEF0
8
LLPS-Xim-2153
ENSXMAG00000018260.2
M4AV04
9
LLPS-Xim-4026
ENSXMAG00000001353.2
A0A3B5R7A8