Takifugu rubripes      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tar-0422
ENSTRUG00000019592.1
A0A3B5K6Q5
2
LLPS-Tar-1697
ENSTRUG00000013399.2
H2UB43
3
LLPS-Tar-1929
ENSTRUG00000018258.2
H2VBZ0
atmin
4
LLPS-Tar-2355
ENSTRUG00000017418.2
H2V605
prkdc
5
LLPS-Tar-2776
ENSTRUG00000003700.2
A0A3B5KLQ4
rad50
6
LLPS-Tar-0893
ENSTRUG00000004357.2
A0A3B5KBZ4
rad51
7
LLPS-Tar-0271
ENSTRUG00000005485.2
H2SL87
rbm45