※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265

  Reviewed (0)  or Unreviewed (10) 

No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Tag-2520	ENSTGUG00000015654.1	H0ZZD7
2		LLPS-Tag-0104	ENSTGUG00000012622.1	H0ZQW0	ATM
3		LLPS-Tag-3060	ENSTGUG00000004575.1	H0Z2B4	ATMIN
4		LLPS-Tag-0063	ENSTGUG00000008533.1	H0ZE28	ATR
5		LLPS-Tag-3625	ENSTGUG00000000008.1	H0YP10	H2AFX
6		LLPS-Tag-0350	ENSTGUG00000001420.1	H0YT62	HDAC1
7		LLPS-Tag-0490	ENSTGUG00000010840.1	H0ZKV6	PRKDC
8		LLPS-Tag-0653	ENSTGUG00000001377.1	H0YT14	RAD50
9		LLPS-Tag-0126	ENSTGUG00000007357.1	H0ZAJ0	RAD51
10		LLPS-Tag-2925	ENSTGUG00000010331.1	H0ZJ98	TP53BP1