※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Sus-1154	ENSSSCG00000025606.2	Q6PQD5	ATM
2		LLPS-Sus-2353	ENSSSCG00000011679.3	F1SKG2	ATR
3		LLPS-Sus-0675	ENSSSCG00000030798.2	A0A287BPC6	FUS
4		LLPS-Sus-0983	ENSSSCG00000003613.3	I3LCK3	HDAC1
5		LLPS-Sus-0594	ENSSSCG00000010489.3	A0A287ANJ6	LOC102166602
6		LLPS-Sus-2233	ENSSSCG00000004766.2	B0M1M6	pigRAD51
7		LLPS-Sus-2059	ENSSSCG00000006274.3	F1RSE6	PRKDC
8		LLPS-Sus-2220	ENSSSCG00000014280.3	A0A287ATD2	RAD50
9		LLPS-Sus-3514	ENSSSCG00000015996.3	A0A287B638	RBM45
10		LLPS-Sus-0514	ENSSSCG00000031949.1	A0A287BBI2	TP53BP1