Sporisorium reilianum      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Spr-0661
sr14292
E7A2J0
Rad51
2
LLPS-Spr-1456
sr10504
E6ZU57
sr10504
3
LLPS-Spr-1387
sr12409
E6ZTF6
sr12409
4
LLPS-Spr-1088
sr15062
E6ZNC8
sr15062