Scophthalmus maximus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scm-0083
ENSSMAG00000001116.1
A0A2U9D233
SMAX5B_001553
2
LLPS-Scm-0339
ENSSMAG00000005431.1
A0A2U9BBI2
SMAX5B_007990
3
LLPS-Scm-1806
ENSSMAG00000001822.1
A0A2U9CDD7
SMAX5B_008547
4
LLPS-Scm-0148
ENSSMAG00000009914.1
A0A2U9AXL0
SMAX5B_011820
5
LLPS-Scm-1845
ENSSMAG00000004161.1
A0A2U9B7N7
SMAX5B_019409
6
LLPS-Scm-3837
ENSSMAG00000016857.1
A0A2U9CSB0
SMAX5B_022127