Pelodiscus sinensis      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pes-0183
ENSPSIG00000012767.1
K7G1R9
2
LLPS-Pes-0603
ENSPSIG00000010890.1
K7FVK7
3
LLPS-Pes-0748
ENSPSIG00000006045.1
K7FFL2
ATM
4
LLPS-Pes-3314
ENSPSIG00000003868.1
K7F7U0
ATMIN
5
LLPS-Pes-2174
ENSPSIG00000017887.1
K7GIT8
ATR
6
LLPS-Pes-0672
ENSPSIG00000009438.1
K7FQT2
FUS
7
LLPS-Pes-1737
ENSPSIG00000017043.1
K7GHL4
PRKDC
8
LLPS-Pes-1993
ENSPSIG00000002884.1
K7F4L8
RBM45
9
LLPS-Pes-1261
ENSPSIG00000009348.1
K7FQI6
TP53BP1