Papio anubis      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Paa-3614
ENSPANG00000018477.2
A0A2I3LWM9
2
LLPS-Paa-4465
ENSPANG00000003668.3
A0A096MUK7
3
LLPS-Paa-1380
ENSPANG00000019174.2
A0A096NCH4
ATM
4
LLPS-Paa-3055
ENSPANG00000010334.2
A0A096NQD8
ATMIN
5
LLPS-Paa-1932
ENSPANG00000005574.2
A0A096NG15
ATR
6
LLPS-Paa-1176
ENSPANG00000021275.2
A0A096NHY1
FUS
7
LLPS-Paa-1864
ENSPANG00000010426.2
A0A096N7R2
H2AFX
8
LLPS-Paa-0117
ENSPANG00000015953.2
A0A096NLV1
MDC1
9
LLPS-Paa-2268
ENSPANG00000025864.3
A0A096NQQ5
PRKDC
10
LLPS-Paa-0451
ENSPANG00000019329.2
A0A2I3M4A9
RAD51
11
LLPS-Paa-2827
ENSPANG00000016088.2
A0A096N3U4
RBM45