Oryzias latipes      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orl-1157
ENSORLG00000027668.1
A0A3B3H6Q9
2
LLPS-Orl-1393
ENSORLG00000009553.2
H2M0P8
atmin
3
LLPS-Orl-1458
ENSORLG00000012184.2
H2M9Q9
atr
4
LLPS-Orl-1392
ENSORLG00000005452.3
H2LLF6
prkdc
5
LLPS-Orl-2175
ENSORLG00000001678.2
A0A3B3HZB0
rad50
6
LLPS-Orl-1751
ENSORLG00000017821.2
H2MU40
rad51
7
LLPS-Orl-2851
ENSORLG00000024508.1
A0A3B3IB19
rbm45
8
LLPS-Orl-0321
ENSORLG00000000116.2
A0A3B3HNU1
tp53bp1