Oryctolagus cuniculus      DNA damage foci


※ DNA damage foci introduction

    DNA damage response proteins such as γH2AX, ATM, 53BP1, RAD51, and the MRE11/RAD50/NBS1 complex, that accumulate and/or are modified in the vicinity of a chromosomal DNA double-strand break to form microscopically visible, subnuclear foci called DNA damage foci, also called (ionizing) radiation‐induced foci (IRIF or RIF) or DNA repair foci. The discovery of DNA damage foci has opened a new dimension to the field of DNA damage signaling. Analysis of the spatiotemporal dynamics of DSB induction and repair in situ or even in live cells has now become a standard method in many different fields (1).

Reference
1. Rothkamm, K., Barnard, S., Moquet, J., Ellender, M., Rana, Z., & Burdak-Rothkamm, S. (2015) DNA damage foci: Meaning and significance. Environ Mol Mutagen, 56(6), 491-504. PMID: 25773265


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orc-1700
ENSOCUG00000014663.3
G1T7X7
ATM
2
LLPS-Orc-3013
ENSOCUG00000007807.2
G1STU3
ATMIN
3
LLPS-Orc-0708
ENSOCUG00000001874.3
G1SGC5
ATR
4
LLPS-Orc-1770
ENSOCUG00000021526.2
G1TV19
FUS
5
LLPS-Orc-1184
ENSOCUG00000003674.2
G1SK67
HDAC1
6
LLPS-Orc-3890
ENSOCUG00000001693.3
G1SFY9
PRKDC
7
LLPS-Orc-4323
ENSOCUG00000025001.2
G1TH13
RAD50
8
LLPS-Orc-0101
ENSOCUG00000016909.3
G1TCL3
RAD51
9
LLPS-Orc-3292
ENSOCUG00000001125.3
G1SET2
RBM45
10
LLPS-Orc-1652
ENSOCUG00000017337.3
G1TDI1
TP53BP1